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Pune University - Molecular Biology - I, April 2010 (Old Course)

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Total No. of Questions : 5] P1001 [Total No. of Pages : 2 [3725] - 32 M.Sc. MICROBIOLOGY MB - 702 : Molecular Biology - I (2005 Pattern) Time : 3 Hours] [Max. Marks : 80 Instructions to the candidates: 1) All questions are compulsory. 2) All questions carry equal marks. 3) Neat well labeled diagrams must be drawn wherever necessary. 4) Use of log tables and electronic pocket calculators is allowed. 5) Assume suitable data, if necessary. Q1) Attempt any two of the following: [16] a) How is higher order structure of chromatin formed? b) Explain ATP dependent and ATP independent events in DNA replication. c) How mismatch repair of heteroduplex leads to gene conversion? Q2) Attempt any two of the following : a) How DNA replication is connected to cell cycle in E.coli? b) What are the characteristics of genetic code? c) [16] How Ras genes finely balanced at the edge of oncogenes? Q3) Comment on any two of the following : a) Error proof DNA repair mechanism. b) Tn 10 transposons. c) [16] C-value paradox. P.T.O.

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Additional Info : M.Sc. MICROBIOLOGY, MB - 702 : Molecular Biology - I (2005 Pattern), Pune University
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