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Complementation is the occurence of a wid type phenotype when two closely related, inyeracting mutant genes are expressed in the same cell.
Transversion of A/G to a pyrimidine would produce a meaningful sense codon.
Its X-linked recessive disorder following criss-cross inheritance.
The other proteins of tight junction are occlaudin, cadherin etc...
In eukaryotes...its called hogness box